Cell line engineering
Kickstart your biologics development journey with our highly-expressing mammalian and microbial cell lines.
What is cell line engineering?
The first step in biologics development, cell line engineering involves the manipulation of mammalian or microbial cell lines to express a desired therapeutic.
Our cell line engineering solutions can help to improve the quality, cost-effectiveness and yield of your biologics products.
Understanding our cell line engineering solutions
What can we offer you?
- Proprietary CHO cell lines
- CHO-K1, CHO GS -/- and CHO DHFR -/- cells for high expression in fed-batch and perfusion processes
- Highly-expressing E. coli cell lines
- Bacterial expression platform E. coli BL21 and plasmid DNA platform E. coli DH5α
- Clonal expression vectors and selection
- Commercial and proprietary vectors for antibiotic, GS (glutamine synthetase) and DHFR (dihydrofolate reductase) selection
Optimize your product expression
Optimize your product expression After engineering your chosen cell line to express your gene of interest (GOI), clone, screen and optimize production with our cell line development solutions.
Safeguard your product development
Collect, characterize and store your engineered cell lines and safeguard your product development with our cell banking solutions.
Why partner with Enzene?
We are a global Continuously Innovative Development and Manufacturing Organization (CIDMO), dedicated to changing the paradigm by which affordable biologic and biosimilar medicines are brought to market. Since Enzene’s inception, our innovative agility has enabled us to continually introduce transformative processes in biologics manufacturing that significantly increase product yields of complex biologics and monoclonal antibodies (mAbs) while reducing the manufacturing footprint and the cost of production.
Game-changing innovation is only the beginning, though. We are Enzene, and that means that our values of innovation, entrepreneurship, respect, candor, excellence, and integrity underscore everything we do from project management and communications to teamwork and ideation. To us, true partnership is about driving biotech innovation while doing so in a way that develops long-lasting trusted partnerships.
Related case studies
The future begins now
Your biologic deserves the most technologically advanced manufacturing process in the industry. And you deserve a new way to think about strategic partnership. Today is just the beginning.