Fully-connected continuous manufacturing™ (EnzeneX™)

Winner of 2025 CPHI Pharma Award for Manufacturing Excellence

Demonstrating a significant innovation over fed-batch and semi-continuous manufacturing processes

Why partner with Enzene?

We are a global Continuously Innovative Development and Manufacturing Organization (CIDMO), dedicated to changing the paradigm by which affordable biologic and biosimilar medicines are brought to market. Since Enzene’s inception, our innovative agility has enabled us to continually introduce transformative processes in biologics manufacturing that significantly increase product yields of complex biologics and monoclonal antibodies (mAbs) while reducing the manufacturing footprint and the cost of production.

Game-changing innovation is only the beginning, though. We are Enzene, and that means that our values of innovation, entrepreneurship, respect, candor, excellence, and integrity underscore everything we do from project management and communications to teamwork and ideation. To us, true partnership is about driving biotech innovation while doing so in a way that develops long-lasting trusted partnerships.

What is EnzeneX™?

We are a global Continuously Innovative Development and Manufacturing Organization (CIDMO), dedicated to changing the paradigm by which affordable biologic and biosimilar medicines are brought to market. Since Enzene’s inception, our innovative agility has enabled us to continually introduce transformative processes in biologics manufacturing that significantly increase product yields of complex biologics and monoclonal antibodies (mAbs) while reducing the manufacturing footprint and the cost of production.

Game-changing innovation is only the beginning, though. We are Enzene, and that means that our values of innovation, entrepreneurship, respect, candor, excellence, and integrity underscore everything we do from project management and communications to teamwork and ideation. To us, true partnership is about driving biotech innovation while doing so in a way that develops long-lasting trusted partnerships.

What can EnzeneX™ do for you?

High-quality production

EnzeneX™ minimizes product contact with cell culture fluid, ensuring high-quality manufacturing. This is crucial for biologics that are prone to degradation including less stable and difficult-to-express proteins.

Cost-effective manufacturing

EnzeneX™ reduces processing costs by approximately 50%, providing you with cost-effective manufacturing. This is achieved with a lower cost of goods and efficient use of resources.

Adaptable design

EnzeneX™ provides flexibility with a minimum 30-50L supply.

The modular and variable bioreactors enable scale-on and scale-out flexibility, allowing you to adapt to changing production needs and optimize your manufacturing capacity.

Increased productivity

EnzeneX™ increases your manufacturing productivity, achieving approximately 10 times higher productivity than traditional fed-batch manufacturing

Reduced emissions

EnzeneX™ increases sustainability by reducing the equipment footprint and carbon footprint of manufacturing processes.

How does EnzeneX™ work?

Discover the science behind our patented and fully validated fully-connected continuous manufacturing™.

EnzeneX™ has enabled us to successfully manufacture commercial monoclonal antibodies (mAbs) and convert biologics from fed-batch production to FCCM™.

Uncover the unique advantages of EnzeneX™